Immunosuppressant
Moderately to severely active UC in adults
Hypersensitivity to the active substance or to any of the excipients; immunodeficient state predisposing to systemic opportunistic infections; patients who in the last 6 months experienced myocardial infarction, unstable angina, stroke, transient ischaemic attack decompensated heart failure requiring hospitalisation or New York Heart Association Class III/IV heart failure; patients with history or presence of second-degree atrioventricular block type ii or third-degree AV block or sick sinus syndrome unless the patient has a functioning pacemaker; severe active infections, active chronic infections such as hepatitis and tuberculosis; active malignancies; severe hepatic impairment; during pregnancy and in women of childbearing potential not using effective contraception.
Oral capsule
Dose: Initially 0.23mg once daily on days 1–4, then increased to 0.46 mg once daily on days 5–7, then increased to 0.92 mg once daily from day 8
0.23mg capsules (4), £CS; 0.46mg (3), £CS; 0.92mg (28), £1,373.00
£CS-£1373.00