Immunosuppressant
Moderately to severely active UC in adults
Active malignancy; heart failure, stroke or unstable angina in previous six months; immunodeficiency; severe active infection. Use with caution in elderly patients; cerebrovascular disease; chronic obstructive pulmonary disease; severe respiratory disease; severe sleep aponoea; diabetes; risk factors for intection; uncontrolled high blood pressure; retinal disease; uveitis. Avoid during pregnancy and breasteeding and in severe hepatic impairment. | Potential side effects: Slow heartbeat; headache; high or low blood pressure; increased risk of infection; low white blood cell count; peripheral oedema
Oral capsule
Dose: Initially 0.23mg once daily on days 1–4, then increased to 0.46 mg once daily on days 5–7, then increased to 0.92 mg once daily from day 8
0.23mg capsules (4), no price; 0.46mg (3), no price; 0.92mg (28), £1,373.00
Thiopurine
Thiopurine
Immunosuppressant
See generic methotrexate listing for indications, contraindications, side effects and dose
See generic methotrexate listing for indications, contraindications, side effects and dose
See generic methotrexate listing for indications, contraindications, side effects and dose